Cialis is nothing but a PDE5 inhibitor which is a drug used in order to block the effect of PDE5 ( phosphodiesterase type 5 ) in the muscle cells which line the blood vessels of the penis. To put it in simple words, it is used to treat erectile dysfunction (ED). Apart from that it is also used in treating signs of benign prostatic hyperplasia when seen along with ED. Cialis soft tabs are also called Super Viagra as they act faster and longer.
MODE OF ACTION
Since the mode of administration of this drug is sublingual, its mechanism of action is much different than the conventional ones. it gets absorbed by the body at a much faster rate from blood vessels present under the tongue through osmosis, thereby it does not have to go through the digestive system. This drug stimulates dopamine receptors present in the brain, thereby transmitting the excitatory signals to the spinal cord, sacral parasympathetic nucleus which in turn stimulates the sacral nerves which supply the penis.
HISTORY OF CIALIS
Developed by a biotechnological firm situated in US called Icos and was acquired by Eli Lilly and Company.
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HOW TO USE IT?
Although it varies from one person to another, the median mode of onset of these drugs is 15-20 minutes before having sex, unlike oral medicines which take 45 minutes to 1 hour. Keep the soft tab sublingially and the diffusion will start instantly and keep it untill it gets disappeared. There is no compulsion of not eating foodstuffs which can alter the absorption of the drug.
DOSAGE
Available in 10mg and 20 mg pills, however the 10mg pill is the commonly prescribed dosage. To start with, the 10mg pill is prescribed and it may be increased or decreased according to the results. It is available in various flavors such as strawberry, lemon, mint and banana. Usually taking one every 3 days is more than enough. The pill is a square orange or yellowish-orange colored and is engraved with a ‘C’. Its half life is 18 hours, thereby its mode of action is longer compared to conventional drugs.
SIDE EFFECTS
DRUG INTERACTIONS
One of the most absolute contraindication of this drug is the use of Organic Nitrates. PDE5 inhibitors can cause transient low blood pressure. Using organic nitrates within 48 hours of the consumption of Cialis Soft. Hence it is important to consult your doctor before starting this medication as it may interfere with the action of Nitrates and cause angina.
HOW TO BUY IT
It is available online on various major pharmacies. It is not available over the counter.
GENERIC NAME
The generic name of this drug is Tadalafil and it;s active content is Tadalafil Citrate. It’s sale as a generic has not been approved as of now.
PRICE ONLINE in Australia
Cialis soft ~ $2.20 price per pill in Melbourne
Available in 10, 20, 30, 60, 90, 120 and 180 pills packs.
I have been working in General Practice since 2006.
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